The ___________________________ and the ________________________ gland (also called "hypophysis") are part of the ____________________ system and the _______________________ system. Together, they produce and control the release of many _____________________. Although the ______________________ is often considered the "master gland" it is really controlled by the ________________________ above it.
The pituitary gland has an ______________________ lobe and a ____________________ lobe and each produces/releases different hormones.
Clusters of neurosecretory cells (neuro-endocrine cells) in the _____________________ produce the 2 hormones _____________________ and ________________________ which move down axons to axon endings in the ___________________ lobe of the pituitary gland where they are stored. When the hypothalamus is stimulated, AP's travel down the axons and the hormones are released from the ___________________ pituitary into the bloodstream.
One hormone, __________________________ (_____), acts on the ____________________ (it's target organ) causing water to be conserved (reabsorbed). This has important effects on blood pressure, blood volume, etc.
The other hormone, ______________________, acts on smooth muscle of the __________________ glands causing milk to be released during lactation and on the _______________________ promoting childbirth.
The release of hormones produced by the _______________________ lobe of the pituitary are controlled by "__________________" and "___________________" hormones made in the hypothalamus. When the hypothalamus secretes releasing hormones into nearby capillaries, the hormones travel through vessels in the stalk (________________________) connecting the hypothalamus and pituitary. The hormones reach the pituitary and either stimulate or inhibit hormone release from the anterior lobe.
| Hypothalamic Releasing Hormone | Anterior Pituitary Hormone Stimulated | Overall Actions of Pituitary Hormone |
| | STH (GH) | |
| CRH (corticotropin releasing hormone) | ||
| | TSH | |
| GnRH (gonadotropin releasing hormone) | ||
| PRLRH (prolactin releasing hormone) |
Negative feedback is very common in hormonal pathways. When a stimulus causes the release of a hormone, the level of the hormone increases. As the hormonal effect kicks in, the release of the hormone is adjusted to match the requirement.