Protein Synthesis 1

Protein Synthesis 2


Now it's time to put everything together and look at the full process of Protein Synthesis: Transcription + Translation. This begins with DNA in the nucleus and ends with the final protein in the cytoplasm.

To do this we need to be able to read the genetic code just as tRNA can. Since each 3-base sequence, or codon, of mRNA codes for ONE amino acid, we look up the amino acid in a codon table (ie. we read what the mRNA codons are coding for).

To use a codon table in general, start with the first mRNA base in the codon and find the first column of the table. Then find the second mRNA base and find the second column. Your choice of amino acid is now constrained to the area in the shared region of column 1 and 2. Now find the third mRNA base and follow it to the specific amino acid. Note the 3 letter abbreviation of the amino acid (ie. HIS = Histidine).

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The DNA sequence below codes for a small portion of a protein. Transcribe the DNA to produce mRNA and translate the mRNA using tRNA's into the correct amino acids. Then identify the protein. Refer to the codon table and amino acid sequences.
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Amino Acid Sequence
  1. How many amino acids are coded for by the DNA?


  2. What protein does this DNA code for?


  3. If instead of ACT, the first DNA triplet was ACG, which amino acid would be coded for?


  4. What amino acid is carried by a tRNA with the anticodon, GUA?


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© Copyright 2008, E. Kimmel